Merkel cell carcinoma is a rare neoplasm whose optimal management has not been clearly defined. We describe the treatment of 5 patients with Merkel cell carcinoma and their histological features, and review the literature on this neoplasm. We also attempt to correlate the presence of the Ki67 antigen with tumour prognosis and highlight the important role of immunocytochemistry in the diagnosis but, contrary to our expectations, not in the evaluation of tumour prognosis. We suggest that the multimodal approach treatment is indicated in patients with tumour recurrence or locoregional disease.
|Number of pages||9|
|Publication status||Published - 1996|
- Merkel cell carcinoma
- Neuroendocrine carcinoma of the skin
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