Merkel cell tumour. Update on histological features and management

M. G. Tucci, M. Giangiacomi, I. Cataldi, M. M. Tappa, B. Rezai, G. Ricotti

Research output: Contribution to journalArticlepeer-review


Merkel cell carcinoma is a rare neoplasm whose optimal management has not been clearly defined. We describe the treatment of 5 patients with Merkel cell carcinoma and their histological features, and review the literature on this neoplasm. We also attempt to correlate the presence of the Ki67 antigen with tumour prognosis and highlight the important role of immunocytochemistry in the diagnosis but, contrary to our expectations, not in the evaluation of tumour prognosis. We suggest that the multimodal approach treatment is indicated in patients with tumour recurrence or locoregional disease.

Original languageEnglish
Pages (from-to)145-153
Number of pages9
JournalSkin Cancer
Issue number2
Publication statusPublished - 1996


  • Merkel cell carcinoma
  • MIB-1
  • Neuroendocrine carcinoma of the skin
  • Surgery

ASJC Scopus subject areas

  • Dermatology
  • Oncology

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