Mesenteric fibromatosis. Case report

A. Giuliani, M. Demoro, A. Ciardi, M. Scimò, F. Galati, M. T. Lonardo, Gaspare Galati

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Deep fibromatosis is a rare locally aggressive but not metastasizing proliferation. Intra-abdominal fibromatosis (IAF) occurs either in association with Gardner's syndrome or as a sporadic event and presents in most cases differential diagnostic problems with myofibroblastic or fibroblastic tumors, characterized by a more aggressive biological behaviour such as gastrointestinal stromal tumors (GISTs). In absence of loco-regional and/or distant metastasis differential diagnosis may be difficult and represents a topical issue, since it influences treatment choice. We describe the case of a patient with sporadic IAF in which the tumor locally involved the mesentery and presented no loco-regional and distant spread. On histology, some morphological features of the neoplasm were in common with a GIST. Definitive diagnosis was made, postoperatively, on the basis of immunohistochemical findings.

Original languageEnglish
Pages (from-to)425-428
Number of pages4
JournalJournal of Experimental and Clinical Cancer Research
Issue number3
Publication statusPublished - Sep 2007


  • Gardner syndrome
  • Gastrointestinal stromal tumor
  • Mesenteric fibromatosis

ASJC Scopus subject areas

  • Cancer Research
  • Oncology


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