Meta-analysis: The fashion of summing-up evidence. Part I. Rationale and conduct

R. D. Gelber, A. Goldhirsch

Research output: Contribution to journalArticlepeer-review


Meta-analysis is the process of formally combining the quantitative results of separate studies in order to increase the statistical precession of estimated effects. It has become fashionable when individual studies fail to yield conclusive results. A recent update of meta-analysis (overview) for treatments of patients with early breast cancer motivated this commentary to discuss the rationale, principles of conduct, statistical methods, and graphical display for summing up results. In part II we will approach the issue of interpretation and use of overview data.

Original languageEnglish
Pages (from-to)461-468
Number of pages8
JournalAnnals of Oncology
Issue number7
Publication statusPublished - 1991

ASJC Scopus subject areas

  • Cancer Research
  • Statistics, Probability and Uncertainty
  • Applied Mathematics
  • Hematology
  • Oncology
  • Public Health, Environmental and Occupational Health
  • Neuropsychology and Physiological Psychology

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