Metabolic acidosis in renal transplantation: Neglected but of potential clinical relevance

Research output: Contribution to journalArticle

Abstract

Chronic metabolic acidosis (CMA) is a common complication of the more advanced stages of chronic kidney diseases (CKD), and is associated with morbidity and mortality of CKD patients and possibly with the progression of renal disease. Nevertheless, there is limited evidence or information on the prevalence, the potential causal factors, the clinical impact and the effects of correction of CMA in kidney transplant recipients. In this review, we briefly look at the more relevant, though scanty, studies which have, over time, addressed the above-mentioned points, with the hope that in the future the interest of transplant nephrologists and surgeons will grow towards this unreasonably neglected issue.

Original languageEnglish
Pages (from-to)730-736
Number of pages7
JournalNephrology Dialysis Transplantation
Volume31
Issue number5
DOIs
Publication statusPublished - May 1 2016

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Acidosis
Chronic Renal Insufficiency
Kidney Transplantation
Kidney
Disease Progression
Morbidity
Transplants
Mortality
Nephrologists
Surgeons
Transplant Recipients

Keywords

  • allograft dysfunction
  • metabolic acidosis
  • renal transplantation

ASJC Scopus subject areas

  • Nephrology
  • Transplantation

Cite this

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AB - Chronic metabolic acidosis (CMA) is a common complication of the more advanced stages of chronic kidney diseases (CKD), and is associated with morbidity and mortality of CKD patients and possibly with the progression of renal disease. Nevertheless, there is limited evidence or information on the prevalence, the potential causal factors, the clinical impact and the effects of correction of CMA in kidney transplant recipients. In this review, we briefly look at the more relevant, though scanty, studies which have, over time, addressed the above-mentioned points, with the hope that in the future the interest of transplant nephrologists and surgeons will grow towards this unreasonably neglected issue.

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