Alterazioni metaboliche e approccio terapeutico nei pazienti in terapia HAART

Translated title of the contribution: Metabolic alterations and therapeutic approach in patients with HAART therapy

Research output: Contribution to journalArticlepeer-review

Abstract

The introduction of highly active antiretroviral therapy (HAART) has dramatically reduced mortality from HIV infection. However, several studies have suggested an association between protease inhibitors (PIs), which are integral components of most HAART regimens, and metabolic disturbances (mainly dyslipidaemia) that may increase atherosclerotic burden and the risk of cardiovascular events. There is a number of strategies for managing HAART-related dyslipidaemia, and their advantages and disadvantages should be considered when treating HIV infected patients. In this review, we summarize current knowledge of cardiovascular prevention in these conditions, with emphasis on controlling hypertriglyceridaemia.

Translated title of the contributionMetabolic alterations and therapeutic approach in patients with HAART therapy
Original languageItalian
Pages (from-to)87-96
Number of pages10
JournalTrends in Medicine
Volume7
Issue number2
Publication statusPublished - Apr 2007

ASJC Scopus subject areas

  • Internal Medicine
  • Pharmacology (medical)

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