Metabolic approach to ischemic heart disease in the elderly

Research output: Contribution to journalArticle


A 79-year-old hypertensive, diabetic woman with known ischemic heart disease, previously revascularized, was referred to our Cardiology Department because of effort-induced dyspnoea associated with bilateral calf stiffness during a walk at high altitude. A thallium scan with intravenous (i.v.) dipyridamole stress showed a fixed inferior perfusion defect and a reversible perfusion defect in the posterior and lateral wall. Medical therapy was optimized before undergoing further interventional procedures. Anti-hypertensive medications were optimized and anti-anginal therapy implemented with trimetazidine. The patient also began a cardiac rehabilitation program. After 2 weeks, dyspnoea with effort disappeared, and after 3 months her exercise capacity improved by 50%.

Original languageEnglish
Pages (from-to)32-34
Number of pages3
JournalHeart and Metabolism
Issue number52
Publication statusPublished - 2011



  • Arterial peripheral disease
  • Elderly
  • Ischemic heart disease
  • Trimetazidine

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Endocrinology, Diabetes and Metabolism

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