METABOLIC BEHAVIOUR OF INORGANIC FORMS OF ANTIMONY IN THE RAT.

J. Edel, E. Marafante, E. Sabbioni, L. Manzo

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Different aspects of the metabolism of Sb in rats have been investigated by neutron activation analysis and radiotracer methods. An obvious accumulation of Sb was observed in the blood of untreated rats as a function of age probably due to interactions with red blood cell components. Differences were found in the metabolic pathways of low doses of Sb**3** plus and Sb**5** plus species. While Sb**3** plus ions become strongly bound to the RBC and are excreted mainly via feces the Sb**5** plus ions are essentially present in a dialyzable form in the plasma with an higher level of excretion mainly via urine. Other mechanisms such as via the biliary system and a direct transfer into the gut are also involved in the elimination of Sb.

Original languageEnglish
Title of host publicationUnknown Host Publication Title
PublisherCEP Consultants Ltd
Pages574-577
Number of pages4
ISBN (Print)0905941071
Publication statusPublished - 1983

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Edel, J., Marafante, E., Sabbioni, E., & Manzo, L. (1983). METABOLIC BEHAVIOUR OF INORGANIC FORMS OF ANTIMONY IN THE RAT. In Unknown Host Publication Title (pp. 574-577). CEP Consultants Ltd.