Le demenze da cause metabolico-nutrizionali, da disfunzioni endocrine e da agenti tossici: Una rivisitazione

Translated title of the contribution: Metabolic, endocrine and toxic dementias: A review

Alfredo Costa, Giorgio Bono, Silvano Cristina, Elena Sinforiani

Research output: Contribution to journalArticlepeer-review


Dementia, a syndrome of acquired cognitive deterioration, is a multifactorial condition which can be permanent or reversible. This review is focused on cognitive disturbances or overt dementia syndromes associated with metabolic factors (i.e. electrolytic changes, metabolic diseases, nutritional disorders, alcoholism), endocrine diseases (i.e. hypothyroidism, Cushing's disease, hypoestrogenic conditions) and exposure to toxic factors (i.e. metals, solvents and drugs). Some of these cognitive disorders appear to be reversible with early diagnosis and proper treatment, although this may occur less frequently than previously reported. Treatable causes of dementia should therefore be sought in all patients presenting with cognitive impairment, as suggested by the guidelines currently used. Recent advances in the field of secondary dementias are also included in this review, with particular regard to endocrine dementias.

Translated title of the contributionMetabolic, endocrine and toxic dementias: A review
Original languageItalian
Pages (from-to)72-84
Number of pages13
JournalNuova Rivista di Neurologia
Issue number3
Publication statusPublished - May 1999

ASJC Scopus subject areas

  • Clinical Neurology


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