Metabolic syndrome across Europe: Different clusters of risk factors

Angelo Scuteri, Stephane Laurent, Francesco Cucca, John Cockcroft, Pedro Guimaraes Cunha, Leocadio Rodriguez Mañas, Francesco U Mattace Raso, Maria Lorenza Muiesan, Ligita Ryliškyte, Ernst Rietzschel, James Strait, Charalambos Vlachopoulos, Henry Völzke, Edward G. Lakatta, Peter M. Nilsson

Research output: Contribution to journalArticlepeer-review


Background: Metabolic syndrome (MetS) remains a controversial entity. Specific clusters of MetS components - rather than MetS per se - are associated with accelerated arterial ageing and with cardiovascular (CV) events. To investigate whether the distribution of clusters of MetS components differed cross-culturally, we studied 34,821 subjects from 12 cohorts from 10 European countries and one cohort from the USA in the MARE (Metabolic syndrome and Arteries REsearch) Consortium. Methods: In accordance with the ATP III criteria, MetS was defined as an alteration three or more of the following five components: elevated glucose (G), fasting glucose ≥110 mg/dl; low HDL cholesterol, 102 cm for men or >88 cm for women. Results: MetS had a 24.3% prevalence (8468 subjects: 23.9% in men vs. 24.6% in women, p

Original languageEnglish
Pages (from-to)486-491
Number of pages6
JournalEuropean Journal of Preventive Cardiology
Issue number4
Publication statusPublished - Apr 15 2015


  • Blood pressure
  • epidemiology
  • Europe
  • glucose
  • HDL cholesterol
  • metabolic syndrome
  • triglycerides
  • waist circumference

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Epidemiology


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