Metabolic Syndrome and psoriatic arthritis: considerations for the clinician

Francesco Caso, Maria Sole Chimenti, Luca Navarini, Piero Ruscitti, Rosario Peluso, Nicolò Girolimetto, Antonio Del Puente, Roberto Giacomelli, Raffaele Scarpa, Luisa Costa

Research output: Contribution to journalArticlepeer-review

Abstract

Introduction: Metabolic Syndrome (MetS) is strictly interconnected with systemic inflammation, and increased evidence has described a close link between this condition and Psoriatic Arthritis (PsA).Areas covered: This review summarizes main studies exploring clinical aspects and prevalence of MetS in PsA cohorts. Further, there is accumulating evidence showing shared inflammatory pathways between MetS, its components, and PsA.Expert opinion: The high prevalence of MetS in PsA highlights the need for screening, evaluation, and close monitoring of MetS and its components (namely, diabetes mellitus, obesity, hypertension, and dyslipidemia) in psoriatic patients.Further studies should focus on the pathogenetic link between MetS and PsA. More studies are required to identify appropriate algorithms for the assessment and management of MetS in PsA patients.

Original languageEnglish
Pages (from-to)409-420
Number of pages12
JournalExpert Review of Clinical Immunology
Volume16
Issue number4
DOIs
Publication statusPublished - Apr 2020
Externally publishedYes

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