Metabolic syndrome as a risk factor for deep vein thrombosis after acute cardiac conditions

Marco Ambrosetti, Walter Ageno, Mario Salerno, Roberto F E Pedretti, Jorge A. Salerno-Uriarte

Research output: Contribution to journalArticlepeer-review


The metabolic syndrome (MS), a cluster of cardiovascular risk factors known to be associated with type II diabetes and arterial disease, has been recently reported to be associated with venous thromboembolism (VTE). In this case-control study MS was tested as a potential risk factor for deep vein thrombosis (DVT) after acute coronary syndromes (ACS) and acute heart failure (AHF). Globally, 86 patients with objectively diagnosed DVT during cardiac rehabilitation after ACS and AHF were compared with a sex and age-matched population of cardiac patients without objectively confirmed DVT. MS was significantly associated to the presence of DVT (OR 2.38; 95% CI 1.64, 3.12), independent from type of cardiac event, prolonged hospitalization, and obesity. Among single determinants of MS, only hypertriglyceridemia was significantly associated with VTE. The presence of MS could increase the risk of VTE after acute cardiac events, thus affecting morbidity and mortality in this patient population.

Original languageEnglish
Pages (from-to)815-818
Number of pages4
JournalThrombosis Research
Issue number6
Publication statusPublished - 2007


  • Acute coronary syndrome
  • Deep vein thrombosis
  • Heart failure
  • Metabolic syndrome

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Hematology


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