TY - JOUR
T1 - Metabolic syndrome as a risk factor for deep vein thrombosis after acute cardiac conditions
AU - Ambrosetti, Marco
AU - Ageno, Walter
AU - Salerno, Mario
AU - Pedretti, Roberto F E
AU - Salerno-Uriarte, Jorge A.
PY - 2007
Y1 - 2007
N2 - The metabolic syndrome (MS), a cluster of cardiovascular risk factors known to be associated with type II diabetes and arterial disease, has been recently reported to be associated with venous thromboembolism (VTE). In this case-control study MS was tested as a potential risk factor for deep vein thrombosis (DVT) after acute coronary syndromes (ACS) and acute heart failure (AHF). Globally, 86 patients with objectively diagnosed DVT during cardiac rehabilitation after ACS and AHF were compared with a sex and age-matched population of cardiac patients without objectively confirmed DVT. MS was significantly associated to the presence of DVT (OR 2.38; 95% CI 1.64, 3.12), independent from type of cardiac event, prolonged hospitalization, and obesity. Among single determinants of MS, only hypertriglyceridemia was significantly associated with VTE. The presence of MS could increase the risk of VTE after acute cardiac events, thus affecting morbidity and mortality in this patient population.
AB - The metabolic syndrome (MS), a cluster of cardiovascular risk factors known to be associated with type II diabetes and arterial disease, has been recently reported to be associated with venous thromboembolism (VTE). In this case-control study MS was tested as a potential risk factor for deep vein thrombosis (DVT) after acute coronary syndromes (ACS) and acute heart failure (AHF). Globally, 86 patients with objectively diagnosed DVT during cardiac rehabilitation after ACS and AHF were compared with a sex and age-matched population of cardiac patients without objectively confirmed DVT. MS was significantly associated to the presence of DVT (OR 2.38; 95% CI 1.64, 3.12), independent from type of cardiac event, prolonged hospitalization, and obesity. Among single determinants of MS, only hypertriglyceridemia was significantly associated with VTE. The presence of MS could increase the risk of VTE after acute cardiac events, thus affecting morbidity and mortality in this patient population.
KW - Acute coronary syndrome
KW - Deep vein thrombosis
KW - Heart failure
KW - Metabolic syndrome
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U2 - 10.1016/j.thromres.2007.02.005
DO - 10.1016/j.thromres.2007.02.005
M3 - Article
C2 - 17509670
AN - SCOPUS:34548695441
VL - 120
SP - 815
EP - 818
JO - Thrombosis Research
JF - Thrombosis Research
SN - 0049-3848
IS - 6
ER -