TY - JOUR
T1 - Metabolic syndrome in the Pressioni Arteriose Monitorate E Loro Associazioni (PAMELA) study
T2 - Daily life blood pressure, cardiac damage, and prognosis
AU - Mancia, Giuseppe
AU - Bombelli, Michele
AU - Corrao, Giovanni
AU - Facchetti, Rita
AU - Madotto, Fabiana
AU - Giannattasio, Cristina
AU - Trevano, Fosca Quarti
AU - Grassi, Guido
AU - Zanchetti, Alberto
AU - Sega, Roberto
PY - 2007/1
Y1 - 2007/1
N2 - The prevalence of the metabolic syndrome (National Cholesterol Education Program Adult Treatment Panel III criteria) and its relationships with daily life blood pressures, cardiac damage, and prognosis were determined in 2013 subjects from a Northern Italian population aged 25 to 74 years. Home blood pressure, 24-hour blood pressure, and left ventricular mass index (echocardiography) were also measured. Cardiovascular and noncardiovascular deaths were registered over 148 months. Metabolic syndrome was found in 16.2% of the sample, an office blood pressure elevation being the most frequent (95.4%) and the blood glucose abnormality the least frequent (31.5%) component. There was in metabolic syndrome a frequent elevation in home and/or 24-hour average blood pressure, as well as a greater left ventricular mass index and prevalence of left ventricular hypertrophy, which was manifest even when data were adjusted for between-group differences, including blood pressure. The adjusted risk of cardiovascular and all-cause mortality was greater in metabolic syndrome subjects (+71.0% and +37.0%; P
AB - The prevalence of the metabolic syndrome (National Cholesterol Education Program Adult Treatment Panel III criteria) and its relationships with daily life blood pressures, cardiac damage, and prognosis were determined in 2013 subjects from a Northern Italian population aged 25 to 74 years. Home blood pressure, 24-hour blood pressure, and left ventricular mass index (echocardiography) were also measured. Cardiovascular and noncardiovascular deaths were registered over 148 months. Metabolic syndrome was found in 16.2% of the sample, an office blood pressure elevation being the most frequent (95.4%) and the blood glucose abnormality the least frequent (31.5%) component. There was in metabolic syndrome a frequent elevation in home and/or 24-hour average blood pressure, as well as a greater left ventricular mass index and prevalence of left ventricular hypertrophy, which was manifest even when data were adjusted for between-group differences, including blood pressure. The adjusted risk of cardiovascular and all-cause mortality was greater in metabolic syndrome subjects (+71.0% and +37.0%; P
KW - Blood pressure
KW - Cardiac hypertrophy
KW - Cardiovascular morbidity
KW - Cardiovascular mortality
KW - Metabolic syndrome
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U2 - 10.1161/01.HYP.0000251933.22091.24
DO - 10.1161/01.HYP.0000251933.22091.24
M3 - Article
C2 - 17130308
AN - SCOPUS:33847630752
VL - 49
SP - 40
EP - 47
JO - Hypertension
JF - Hypertension
SN - 0194-911X
IS - 1
ER -