Metabolism of exogenous cortisol in humans-I. Diurnal variation in plasma disappearance rate

P. L. Morselli, V. Marc, S. Garattini, M. Zaccala

Research output: Contribution to journalArticle

Abstract

A variation in the rate of disappearance from plasma, at different times of the day, has been observed for exogenous Cortisol in humans after i.v. administration. This appears to correlate with the endogenous cortisol plasma levels. The possibility of a circadian fluctuation of drug metabolizing enzyme activities in man is discussed.

Original languageEnglish
Pages (from-to)1643-1647
Number of pages5
JournalBiochemical Pharmacology
Volume19
Issue number5
DOIs
Publication statusPublished - 1970

ASJC Scopus subject areas

  • Pharmacology

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