Metachronous bladder metastases from renal cell carcinoma: A case report and review of the literature

S. Melegari, G. Albo, B. Rocco, F. Verweij, M. Abbinante, O. De Cobelli

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Introduction: adrenal gland, parotid gland, pharynx, eye and bladder are rare localizations of metastases of renal cell carcinoma (RCC). We report a case of metachronous RCC metastases to the bladder in a patient with a medical history of transitional cell carcinoma (TCC) of the bladder. Materials and methods: a case study and review of the relevant literature are presented. Results: during a follow-up cystoscopy examination following treatment of TCC, a single 5-mm lesion was detected and endoscopically resected. The histology of the resected sample was confirmed to be RCC, comparable to a primary kidney cancer and not recurrent TCC. Conclusion: the patient had a probability of metastases three years after nephrectomy of 62.9%. Survival rates following single metastasectomy are 60% and 38% at three and five years, respectively; metachronous diagnosis has a better prognosis than synchronous. During RCC follow-up, each lesion should be considered as a possible metastasis of RCC.

Original languageEnglish
Article number175
Issue number1
Publication statusPublished - Mar 18 2010

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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