Metachronous pulmonary metastases resection in patients with Ewing's sarcoma initially treated with adjuvant or neoadjuvant chemotherapy

G. Bacci, A. Briccoli, P. Picci, S. Ferrari

Research output: Contribution to journalArticlepeer-review

Abstract

55 patients with Ewing's sarcoma of bone, treated at our Institution with adjuvant or neoadjuvant chemotherapy between 1972 and 1990, relapsed with pulmonary metastases alone. 12 of these patients-selected according to their long disease-free interval before relapse, monolaterality of the lesions, small numbers of metastatic nodules, resectability and refusal to undergo further chemotherapic treatments-were treated with surgical resection of the metastatic lesions and with no additional radio- or chemotherapy. At a follow-up ranging between 3 and 14 years (mean 9 years), 5 of these 12 patients (42%), were continuously free of disease, whereas the remaining 7 patients died with uncontrolled disease 12-39 months (mean 22 months) after thoracotomy. These results seem to indicate that an aggressive surgical approach should be considered for a selected group of Ewing's sarcoma patients who relapse with only lung metastases.

Original languageEnglish
Pages (from-to)999-1001
Number of pages3
JournalEuropean Journal of Cancer
Volume31
Issue number6
DOIs
Publication statusPublished - 1995

Keywords

  • Ewing's sarcoma
  • pulmonary metastases
  • surgery
  • survival

ASJC Scopus subject areas

  • Cancer Research
  • Oncology
  • Hematology

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