Abstract
55 patients with Ewing's sarcoma of bone, treated at our Institution with adjuvant or neoadjuvant chemotherapy between 1972 and 1990, relapsed with pulmonary metastases alone. 12 of these patients-selected according to their long disease-free interval before relapse, monolaterality of the lesions, small numbers of metastatic nodules, resectability and refusal to undergo further chemotherapic treatments-were treated with surgical resection of the metastatic lesions and with no additional radio- or chemotherapy. At a follow-up ranging between 3 and 14 years (mean 9 years), 5 of these 12 patients (42%), were continuously free of disease, whereas the remaining 7 patients died with uncontrolled disease 12-39 months (mean 22 months) after thoracotomy. These results seem to indicate that an aggressive surgical approach should be considered for a selected group of Ewing's sarcoma patients who relapse with only lung metastases.
| Original language | English |
|---|---|
| Pages (from-to) | 999-1001 |
| Number of pages | 3 |
| Journal | European Journal of Cancer |
| Volume | 31 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1995 |
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Keywords
- Ewing's sarcoma
- pulmonary metastases
- surgery
- survival
ASJC Scopus subject areas
- Cancer Research
- Oncology
- Hematology
Cite this
Metachronous pulmonary metastases resection in patients with Ewing's sarcoma initially treated with adjuvant or neoadjuvant chemotherapy. / Bacci, G.; Briccoli, A.; Picci, P.; Ferrari, S.
In: European Journal of Cancer, Vol. 31, No. 6, 1995, p. 999-1001.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Metachronous pulmonary metastases resection in patients with Ewing's sarcoma initially treated with adjuvant or neoadjuvant chemotherapy
AU - Bacci, G.
AU - Briccoli, A.
AU - Picci, P.
AU - Ferrari, S.
PY - 1995
Y1 - 1995
N2 - 55 patients with Ewing's sarcoma of bone, treated at our Institution with adjuvant or neoadjuvant chemotherapy between 1972 and 1990, relapsed with pulmonary metastases alone. 12 of these patients-selected according to their long disease-free interval before relapse, monolaterality of the lesions, small numbers of metastatic nodules, resectability and refusal to undergo further chemotherapic treatments-were treated with surgical resection of the metastatic lesions and with no additional radio- or chemotherapy. At a follow-up ranging between 3 and 14 years (mean 9 years), 5 of these 12 patients (42%), were continuously free of disease, whereas the remaining 7 patients died with uncontrolled disease 12-39 months (mean 22 months) after thoracotomy. These results seem to indicate that an aggressive surgical approach should be considered for a selected group of Ewing's sarcoma patients who relapse with only lung metastases.
AB - 55 patients with Ewing's sarcoma of bone, treated at our Institution with adjuvant or neoadjuvant chemotherapy between 1972 and 1990, relapsed with pulmonary metastases alone. 12 of these patients-selected according to their long disease-free interval before relapse, monolaterality of the lesions, small numbers of metastatic nodules, resectability and refusal to undergo further chemotherapic treatments-were treated with surgical resection of the metastatic lesions and with no additional radio- or chemotherapy. At a follow-up ranging between 3 and 14 years (mean 9 years), 5 of these 12 patients (42%), were continuously free of disease, whereas the remaining 7 patients died with uncontrolled disease 12-39 months (mean 22 months) after thoracotomy. These results seem to indicate that an aggressive surgical approach should be considered for a selected group of Ewing's sarcoma patients who relapse with only lung metastases.
KW - Ewing's sarcoma
KW - pulmonary metastases
KW - surgery
KW - survival
UR - http://www.scopus.com/inward/record.url?scp=0029001795&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0029001795&partnerID=8YFLogxK
U2 - 10.1016/0959-8049(95)00093-3
DO - 10.1016/0959-8049(95)00093-3
M3 - Article
C2 - 7646936
AN - SCOPUS:0029001795
VL - 31
SP - 999
EP - 1001
JO - European Journal of Cancer
JF - European Journal of Cancer
SN - 0959-8049
IS - 6
ER -