TY - JOUR
T1 - Metastases to the breast
T2 - Role of fine needle cytology samples. Our experience with nine cases in 2 years
AU - Fulciniti, Franco
AU - Losito, S.
AU - Botti, G.
AU - Di Mattia, D.
AU - La Mura, A.
AU - Pisano, C.
AU - Pignata, S.
PY - 2008/4
Y1 - 2008/4
N2 - Background: The increased survival due to the introduction of effective antineoplastic regimens has caused a modification of the natural history of numerous malignancies. Follow-up of neoplastic patients often includes the evaluation of masses in various body sites by fine needle cytology (FNC) in order to rule out cancer recurrence. Besides primary neoplasms, the breast can host a number of metastases: these rarely do have a typical presentation, so FNC is requested for their cytomorphological assessment. Patients and methods: This report describes nine consecutive cases in which a cytopathological diagnosis of metastasis to the breast was carried out on FNC samples. Results: Primary sites were identified on cytomorphological and immunocytochemical bases and were represented by the ovary (three cases), melanoma (two cases), endocervix (one case), endometrium (one case), lung (one case) and prostate (one case). Conclusion: The cytopathological diagnosis of metastatic neoplasms to the breast is not always straightforward, especially in the absence of a clinical history of cancer. The usage of improved cytopathological criteria combined with immunocytochemistry may be of great diagnostic help in the identification of breast metastases.
AB - Background: The increased survival due to the introduction of effective antineoplastic regimens has caused a modification of the natural history of numerous malignancies. Follow-up of neoplastic patients often includes the evaluation of masses in various body sites by fine needle cytology (FNC) in order to rule out cancer recurrence. Besides primary neoplasms, the breast can host a number of metastases: these rarely do have a typical presentation, so FNC is requested for their cytomorphological assessment. Patients and methods: This report describes nine consecutive cases in which a cytopathological diagnosis of metastasis to the breast was carried out on FNC samples. Results: Primary sites were identified on cytomorphological and immunocytochemical bases and were represented by the ovary (three cases), melanoma (two cases), endocervix (one case), endometrium (one case), lung (one case) and prostate (one case). Conclusion: The cytopathological diagnosis of metastatic neoplasms to the breast is not always straightforward, especially in the absence of a clinical history of cancer. The usage of improved cytopathological criteria combined with immunocytochemistry may be of great diagnostic help in the identification of breast metastases.
KW - Breast neoplasms
KW - Clinical cytology
KW - Diagnostic cytopathology of tumors
KW - Fine needle cytology
KW - Metastases to the breast
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U2 - 10.1093/annonc/mdm546
DO - 10.1093/annonc/mdm546
M3 - Article
C2 - 18048381
AN - SCOPUS:41549115845
VL - 19
SP - 682
EP - 687
JO - Annals of Oncology
JF - Annals of Oncology
SN - 0923-7534
IS - 4
ER -