Abstract
A case of somatostatin-producing pancreatic tumor associated with severe insulin-dependent diabetes mellitus and ketoacidotic coma is reported. The tumor, a 10-cm expansile mass arising from the pancreatic tail of a 70-yr-old woman, was first detected by ultrasonography, performed because of abdominal pain, and subsequently confirmed by computed tomography and fine-needle tumor aspiration. Pathologic investigation showed a predominantly solid-trabecular structure with scattered microacini and psammomatous bodies. A large proportion of tumor cells expressed somatostatin and/or calcitonin. Following resection of the primary tumor and three peripancreatic lymph nodes with metastases, the patient recovered rapidly from her diabetic syndrome and remained in substantially good health during a subsequent 8-yr follow-up period, without evidence of tumor recurrence.
| Original language | English |
|---|---|
| Pages (from-to) | 327-333 |
| Number of pages | 7 |
| Journal | Endocrine Pathology |
| Volume | 8 |
| Issue number | 4 |
| Publication status | Published - Dec 1997 |
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Keywords
- Computed tomography
- Diabetes mellitus
- Histopathology
- Ketoacidotic coma
- Pancreatic somatostatinoma
- Ultrasonography
ASJC Scopus subject areas
- Endocrinology
- Endocrinology, Diabetes and Metabolism
- Pathology and Forensic Medicine
Cite this
Metastatic psammomatous somatostatinoma of the pancreas causing severe ketoacidotic diabetes cured by surgery. / Sessa, Fausto; Arcidiaco, Massimo; Valenti, Luigi; Solcia, Marco; Di Maggio, Enrico; Solcia, Enrico.
In: Endocrine Pathology, Vol. 8, No. 4, 12.1997, p. 327-333.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Metastatic psammomatous somatostatinoma of the pancreas causing severe ketoacidotic diabetes cured by surgery
AU - Sessa, Fausto
AU - Arcidiaco, Massimo
AU - Valenti, Luigi
AU - Solcia, Marco
AU - Di Maggio, Enrico
AU - Solcia, Enrico
PY - 1997/12
Y1 - 1997/12
N2 - A case of somatostatin-producing pancreatic tumor associated with severe insulin-dependent diabetes mellitus and ketoacidotic coma is reported. The tumor, a 10-cm expansile mass arising from the pancreatic tail of a 70-yr-old woman, was first detected by ultrasonography, performed because of abdominal pain, and subsequently confirmed by computed tomography and fine-needle tumor aspiration. Pathologic investigation showed a predominantly solid-trabecular structure with scattered microacini and psammomatous bodies. A large proportion of tumor cells expressed somatostatin and/or calcitonin. Following resection of the primary tumor and three peripancreatic lymph nodes with metastases, the patient recovered rapidly from her diabetic syndrome and remained in substantially good health during a subsequent 8-yr follow-up period, without evidence of tumor recurrence.
AB - A case of somatostatin-producing pancreatic tumor associated with severe insulin-dependent diabetes mellitus and ketoacidotic coma is reported. The tumor, a 10-cm expansile mass arising from the pancreatic tail of a 70-yr-old woman, was first detected by ultrasonography, performed because of abdominal pain, and subsequently confirmed by computed tomography and fine-needle tumor aspiration. Pathologic investigation showed a predominantly solid-trabecular structure with scattered microacini and psammomatous bodies. A large proportion of tumor cells expressed somatostatin and/or calcitonin. Following resection of the primary tumor and three peripancreatic lymph nodes with metastases, the patient recovered rapidly from her diabetic syndrome and remained in substantially good health during a subsequent 8-yr follow-up period, without evidence of tumor recurrence.
KW - Computed tomography
KW - Diabetes mellitus
KW - Histopathology
KW - Ketoacidotic coma
KW - Pancreatic somatostatinoma
KW - Ultrasonography
UR - http://www.scopus.com/inward/record.url?scp=26444462574&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=26444462574&partnerID=8YFLogxK
M3 - Article
AN - SCOPUS:26444462574
VL - 8
SP - 327
EP - 333
JO - Endocrine Pathology
JF - Endocrine Pathology
SN - 1046-3976
IS - 4
ER -