Methisoprinol in the treatment of multiple sclerosis. A pilot study

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Twenty-five patients affected by remittent form of multiple sclerosis (MS) were treated with methisoprinol for a period of 2 years. The clinical parameters, recorded during a 2-year observation period preceding onset of therapy, were compared with the analogous measures recorded during treatment. Treatment was associated with significant favourable changes. In fact, there were observed: a reduction in mean annual relapse rate for 22 of 25 patients; an improvement in the clinical status as demonstrated by the reduction of the Kurtzke Disability Status Scale values obtained in 14 of 25 patients; a reduction in the mean period of standard corticosteroid therapy.

Original languageEnglish
Pages (from-to)293-296
Number of pages4
JournalActa Neurologica Scandinavica
Issue number4
Publication statusPublished - 1986

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)


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