Methods of assessment of quality of life

C. F. Donner, M. Carone, G. Bertolotti, A. M. Zotti

Research output: Contribution to journalArticlepeer-review


To measure quality of life (QoL) we can use general health questionnaires or disease-specific questionnaires. The general health questionnaires express a measure of the disturbance to health as seen from the patient's viewpoint. The disease-specific questionnaires focus on a specific disease and its treatment. The general health measures used in chronic obstructive pulmonary disease (COPD) and asthmatic patients are the Quality of Well-Being (QWB) Scale and the Sickness Impact Profile (SIP). The questionnaires developed and validated for asthmatic and COPD patients are: the Chronic Respiratory Disease Questionnaire (CRDQ), the Living With Asthma Questionnaire (LWAQ), the Asthma Quality of Life Questionnaire (AQLQ) and the St. George's Respiratory Questionnaire (SGRQ). COPD patients with chronic hypoxaemia have a very severe airway obstruction. Once the forced expiratory volume in one second (FEV1) falls below 1L, it appears that there is a rapid increase in the impact of the disease on the patient's daily life and well-being. Moreover, hypoxaemia may cause impairment of neuropsychological functioning, compared to control patients. We have examined different questionnaires. However, with the partial exception of the SQRQ, none of them seems to be appropriate for patients with established respiratory failure, on long-term oxygen therapy or mechanical ventilation. Therefore, we found it necessary to develop a new questionnaire, specifically for this group of patients.

Original languageEnglish
Pages (from-to)43-45
Number of pages3
JournalEuropean Respiratory Review
Issue number42
Publication statusPublished - 1997


  • Chronic obstructive pulmonary disease
  • Long-term oxygen therapy
  • Quality of life
  • Respiratory failure

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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