Microablative fractional CO2 laser improves dyspareunia related to vulvovaginal atrophy: A pilot study

Stefano Salvatore, Umberto Leone Roberti Maggiore, Massimo Origoni, Marta Parma, Lavinia Quaranta, Filomena Sileo, Alice Cola, Ilaria Baini, Simone Ferrero, Massimo Candiani, Nicola Zerbinati

Research output: Contribution to journalArticlepeer-review


methods: The intensity of VVA symptoms was recorded for each patient. Patients were administered the Short Form 12 (SF-12) and the female sexual function index (FSFI) to assess quality of life and sexual function, respectively. An objective evaluation of female urogenital health was performed using the Gloria Bachman Vaginal Health Index (VHI).

Results: At 12-week follow-up, the laser treatment was efficacious in improving dyspareunia in 100% of patients included in the study (n = 15). The intensity of dyspareunia significantly decreased from baseline (8.7 ± 1.0) to 12-week follow-up (2.2 ± 1.0; p

Conclusions: This pilot study demonstrated that treatment with the microablative fractional CO2 laser of patients with dyspareunia related to VVA was efficacious at 12-week follow-up.

Objective: This pilot study aimed to assess the efficacy in treating sexually active menopausal patients who had dyspareunia related to vulvovaginal atrophy (VVA). Materials and

Original languageEnglish
Pages (from-to)150-156
Number of pages7
JournalJournal of Endometriosis and Pelvic Pain Disorders
Issue number3
Publication statusPublished - Jul 1 2014


  • Dyspareunia
  • Fractional CO<inf>2</inf> laser
  • Menopause
  • Vaginal atrophy
  • Vaginal dryness

ASJC Scopus subject areas

  • Obstetrics and Gynaecology


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