Microbiology of mycobacterium tuberculosis and a new diagnostic test for TB

Vera Katalinić-Janković, Lucinda Furci, Daniela Maria Cirillo

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Tuberculosis (TB) has been one of the most important human diseases for centuries now. It is mainly caused by Mycobacterium tuberculosis, a highly elusive bacillus. This intracellular pathogen does not possess the classic bacterial virulence factors. However, M. tuberculosis efficiently evades the immune response by complex and manipulative mechanisms, which enable survival for as long as decades. The fight with such a smart rival gives rise to the necessity for early diagnosis and appropriate treatment. The ability to rapidly detect M. tuberculosis in clinical specimens, as well as drug resistance, is essential for the appropriate treatment of TB patients and the prevention of spread of drug-resistant strains. New molecular tools are now used in many countries as part of a standard laboratory diagnosis. It is clear that important advances in TB diagnosis have recently been made and potentially useful new tools are emerging. Nevertheless, there is still a lot to be done, especially in high-burden countries where fast identification and early treatment are needed.

Original languageEnglish
Pages (from-to)8-13
Number of pages6
JournalEuropean Respiratory Monograph
Volume58
DOIs
Publication statusPublished - 2012

Fingerprint

Microbiology
Mycobacterium tuberculosis
Routine Diagnostic Tests
Tuberculosis
Clinical Laboratory Techniques
Virulence Factors
Antigen-Antibody Complex
Drug Resistance
Bacillus
Early Diagnosis
Therapeutics
Survival
Pharmaceutical Preparations

Keywords

  • Diagnostic tools
  • Drug resistance
  • Immunity
  • Latency
  • Mycobacterium tuberculosis
  • Pathogenesis

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Microbiology of mycobacterium tuberculosis and a new diagnostic test for TB. / Katalinić-Janković, Vera; Furci, Lucinda; Cirillo, Daniela Maria.

In: European Respiratory Monograph, Vol. 58, 2012, p. 8-13.

Research output: Contribution to journalArticle

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