Abstract
State-of-the-art screening mammography allows the detection of nonpalpable breast lesions in approximately 30 % of patients. The presence of clustered microcalcifications without evidence of solid tumors usually requires further investigations, mainly biopsy. A 1.5-T magnet with a single breast coil was used to evaluate 32 patients with indeterminate mammography suggestive of microcalcifications prior to surgery. Both spin-echo (SE) and gradient-echo (GE; 2D fast low-angle short [FLASH]) techniques were utilized before and after injection of 0.2 mmol/kg Gd-DTPA. Upon surgery tumor diameters ranged between 3 and 10 mm. Use of MRI demonstrated 87.5 % overall accuracy, 83.3 % sensitivity, and 92.9 % specificity. False-negative MRI results were in situ carcinomas less than 5 mm in size. All the correctly diagnosed carcinomas measured between 5 and 10 mm. Partial volume is probably the greatest limit of this technique and lesions equal to or smaller than 5 mm are only rarely detected. The GE and SE sequences demonstrated comparable results.
| Original language | English |
|---|---|
| Pages (from-to) | 417-422 |
| Number of pages | 6 |
| Journal | European Radiology |
| Volume | 5 |
| Issue number | 4 |
| DOIs | |
| Publication status | Published - Aug 1995 |
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Keywords
- Breast neoplasms, diagnosis
- Breast neoplasms, MR studies
- MRI, Gd-DTPA
- MRI, technology
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
- Radiology Nuclear Medicine and imaging
Cite this
Microcalcifications in clinically normal breast : the value of high field, surface coil, Gd-DTPA-enhanced MRI. / Tesoro-Tess, J. D.; Amoruso, A.; Rovini, D.; Balzarini, L.; Ceglia, E.; Civelli, E.; Trecate, G.; Savio, T.; Musumeci, R.
In: European Radiology, Vol. 5, No. 4, 08.1995, p. 417-422.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Microcalcifications in clinically normal breast
T2 - the value of high field, surface coil, Gd-DTPA-enhanced MRI
AU - Tesoro-Tess, J. D.
AU - Amoruso, A.
AU - Rovini, D.
AU - Balzarini, L.
AU - Ceglia, E.
AU - Civelli, E.
AU - Trecate, G.
AU - Savio, T.
AU - Musumeci, R.
PY - 1995/8
Y1 - 1995/8
N2 - State-of-the-art screening mammography allows the detection of nonpalpable breast lesions in approximately 30 % of patients. The presence of clustered microcalcifications without evidence of solid tumors usually requires further investigations, mainly biopsy. A 1.5-T magnet with a single breast coil was used to evaluate 32 patients with indeterminate mammography suggestive of microcalcifications prior to surgery. Both spin-echo (SE) and gradient-echo (GE; 2D fast low-angle short [FLASH]) techniques were utilized before and after injection of 0.2 mmol/kg Gd-DTPA. Upon surgery tumor diameters ranged between 3 and 10 mm. Use of MRI demonstrated 87.5 % overall accuracy, 83.3 % sensitivity, and 92.9 % specificity. False-negative MRI results were in situ carcinomas less than 5 mm in size. All the correctly diagnosed carcinomas measured between 5 and 10 mm. Partial volume is probably the greatest limit of this technique and lesions equal to or smaller than 5 mm are only rarely detected. The GE and SE sequences demonstrated comparable results.
AB - State-of-the-art screening mammography allows the detection of nonpalpable breast lesions in approximately 30 % of patients. The presence of clustered microcalcifications without evidence of solid tumors usually requires further investigations, mainly biopsy. A 1.5-T magnet with a single breast coil was used to evaluate 32 patients with indeterminate mammography suggestive of microcalcifications prior to surgery. Both spin-echo (SE) and gradient-echo (GE; 2D fast low-angle short [FLASH]) techniques were utilized before and after injection of 0.2 mmol/kg Gd-DTPA. Upon surgery tumor diameters ranged between 3 and 10 mm. Use of MRI demonstrated 87.5 % overall accuracy, 83.3 % sensitivity, and 92.9 % specificity. False-negative MRI results were in situ carcinomas less than 5 mm in size. All the correctly diagnosed carcinomas measured between 5 and 10 mm. Partial volume is probably the greatest limit of this technique and lesions equal to or smaller than 5 mm are only rarely detected. The GE and SE sequences demonstrated comparable results.
KW - Breast neoplasms, diagnosis
KW - Breast neoplasms, MR studies
KW - MRI, Gd-DTPA
KW - MRI, technology
UR - http://www.scopus.com/inward/record.url?scp=0001456809&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0001456809&partnerID=8YFLogxK
U2 - 10.1007/BF00184955
DO - 10.1007/BF00184955
M3 - Article
AN - SCOPUS:0001456809
VL - 5
SP - 417
EP - 422
JO - European Radiology
JF - European Radiology
SN - 0938-7994
IS - 4
ER -