ARLs encompass a heterogeneous group of lymphomas. Their heterogeneity is likely attributed to their microenvironment and varying mechanisms of lymphomagenesis that includes HIV-induced immunosuppression, coinfection with the herpesviruses EBV and HHV8, chronic antigenic stimulation, genetic abnormalities, cytokine release and dysregulation, dendritic cell impairment and angiogenesis.
|Title of host publication||Hodgkin and Non-Hodgkin Lymphomas Seen through Their Microenvironment: Impact on Diagnosis, Prognosis and Innovative Therapy|
|Publisher||Future Medicine Ltd.|
|Number of pages||19|
|ISBN (Print)||9781780845821, 9781780845845|
|Publication status||Published - Jun 1 2015|
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