Microhardness evaluations of the bone growing into porous implants

S. Stea, C. Tarabusi, G. Ciapetti, A. Pizzoferrato, A. Toni, A. Sudanese

Research output: Contribution to journalArticlepeer-review


Small cylinders of a new composite porous material consisting of a dense alumina core coated with two layers of beads of the same material, bonded to each other and to the underlying surface by a high-temperature melting glass have been implanted in the proximal femurs of rabbits. The explants were carried out 1, 4, 6, 8, and 18 weeks after surgery. The bone fragment containing the implant was embedded in methyl methacrylate without performing decalcification, and morphological observations were carried out. These showed that four weeks after surgery it is already possible to observe the development of bone spicules in the implant porosities. Along with these studies, microhardness measurements were carried out by using a microhardness tester connected to an image analyser. The mineralized tissue in close contact with the implant showed, one month after surgery, a compression strength similar to that of healthy bone.

Original languageEnglish
Pages (from-to)252-254
Number of pages3
JournalJournal of Materials Science: Materials in Medicine
Issue number4
Publication statusPublished - Jul 1992

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering(all)
  • Biophysics

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