Micronucleus frequency and cell proliferation in human lymphocytes exposed to 50 Hz sinusoidal magnetic fields

M. R. Scarfi, M. B. Lioi, O. Zeni, M. Della Noce, C. Franceschi, F. Bersani

Research output: Contribution to journalArticle

Abstract

In the present study micronucleus induction and cell proliferation in human peripheral blood lymphocytes cultured in vitro and exposed to 50 Hz sinusoidal magnetic fields for 72 h at different intensities (1.0, 0.75, 0.5, 0.25, and 0.05 mT rms) were investigated. The results obtained from 42 healthy donors aged between 26 and 54 y indicate that, for the field intensities tested, no genotoxic effects were found, as assessed by the cytokinesis-block micronucleus assay. On the contrary, cell proliferation, evaluated by the cytokinesis-block proliferation index, was slightly affected by the field at the intensities tested.

Original languageEnglish
Pages (from-to)244-250
Number of pages7
JournalHealth Physics
Volume76
Issue number3
Publication statusPublished - 1999

Keywords

  • Bioassay
  • Magnetic fields
  • Nonionizing
  • Radiation
  • Tumors

ASJC Scopus subject areas

  • Environmental Science (miscellaneous)
  • Health, Toxicology and Mutagenesis
  • Toxicology
  • Physics and Astronomy (miscellaneous)
  • Public Health, Environmental and Occupational Health
  • Environmental Chemistry
  • Environmental Science(all)

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  • Cite this

    Scarfi, M. R., Lioi, M. B., Zeni, O., Della Noce, M., Franceschi, C., & Bersani, F. (1999). Micronucleus frequency and cell proliferation in human lymphocytes exposed to 50 Hz sinusoidal magnetic fields. Health Physics, 76(3), 244-250.