Microperimetry and fundus autofluorescence in patients with early age-related macular degeneration

Edoardo Midena, Stela Vujosevic, Enrica Convento, Antonio Manfre', Fabiano Cavarzeran, Elisabetta Pitotto

Research output: Contribution to journalArticlepeer-review

Abstract

Background: Early age-related macular degeneration (AMD) has been correlated with different functional alterations, but the exact relationship between fundus lesions and overlying sensitivity is not well known. The aim of this study was to compare fundus-related sensitivity (microperimetry) and fundus autofluorescence (FAF) of the macular area with drusen and pigment abnormalities in early AMD. Methods: 13 consecutive patients with early AMD and visual acuity of 20/20 were studied by means of microperimetry, which automatically analyses macular light differential threshold and fixation patterns. Fundus colour photo and FAF of the macular area were recorded on the same day. Microperimetry was exactly (topographically) superimposed over FAF images. Results: Macular sensitivity significantly decreased over large drusen (11.2 ± 5.6 dB, p

Original languageEnglish
Pages (from-to)1499-1503
Number of pages5
JournalBritish Journal of Ophthalmology
Volume91
Issue number11
DOIs
Publication statusPublished - Nov 2007

ASJC Scopus subject areas

  • Ophthalmology

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