MicroRNAs and prostate cancer

Valeria Coppola, Ruggero De Maria, Désirée Bonci

Research output: Contribution to journalArticle

Abstract

Despite much progress in prostate cancer management, new diagnostic, prognostic and therapeutic tools are needed to predict disease severity, choose among the available treatments and establish more effective therapies for advanced prostate cancer. In the last few years, compelling evidence has documented the role of microRNAs as new broad-spectrum oncogenes or tumour suppressor genes, thus their use as diagnostic, prognostic and therapeutic biomolecules is envisaged. This review extensively and critically summarizes the current knowledge about microRNAderegulation in prostate cancer disease, underlining present limits and future perspectives.

Original languageEnglish
JournalEndocrine-Related Cancer
Volume17
Issue number1
DOIs
Publication statusPublished - Mar 2010

ASJC Scopus subject areas

  • Cancer Research
  • Endocrinology
  • Endocrinology, Diabetes and Metabolism
  • Oncology

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