Microsurgical anatomy in trans-sphenoidal hypophysectomy

J. Hardy, G. Maira

Research output: Contribution to journalArticlepeer-review


The detailed operation reports from 266 patients, suffering from metastatic breast cancer and diabetic retinopathy, who had a transphenoidal open surgical hypophysectomy, have been evaluated with particular attention on the anatomical variations and anomalies which may be related to the pitfalls, difficulties or complications during the ablation of the pituitary gland. In the majority of patients the standard usual well known anatomy of the sellar region was encountered and offered the excellent conditions for successful achievement of the ideal total ablation of the pituitary gland in one piece. Anatomical variations in the sphenoid sinus or sella turcica or adjacent structures are described in detailed statistical data. Some required only slight modification in the standard technique. Others were responsible for increase difficulty. However none of the anatomical variants and pathological findings has ever obliged the surgeon to interrupt the procedure in any single case. No risk of mortality and minimal risk of morbidity are related to this surgical approach to the normal pituitary gland.

Original languageEnglish
Pages (from-to)151-157
Number of pages7
JournalJournal of Neurosurgical Sciences
Issue number2-3
Publication statusPublished - 1977

ASJC Scopus subject areas

  • Clinical Neurology


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