Midterm Results of a Combined Biological and Mechanical Approach for the Treatment of a Complex Knee Lesion

G. Filardo, A. Di Martino, Elizaveta Kon, M. Delcogliano, M. Marcacci

Research output: Contribution to journalArticlepeer-review


Objective: Complex fractures of the tibial plateau are difficult to treat and present a high complication rate. The goal of this report is to describe a combined biological and mechanical approach to restore all morphological and functional knee properties. Methods: We treated a 50-year-old woman, who was affected by a posttraumatic osteochondral lesion and depression of the lateral tibial plateau with knee valgus deviation. The mechanical axis was corrected with a lateral tibial plateau elevation osteotomy, the damaged joint surface was replaced by a recently developed biomimetic osteochondral scaffold, and a hinged dynamic external fixator was applied to protect the graft and at the same time to allow postoperative joint mobilization. Results: A marked clinical improvement was documented at 12 months and further improved up to 5 years, with pain-free full range of motion and return to previous activities. The MRI evaluation at 12 and 24 months showed that the implant remained in site with a hyaline-like signal and restoration of the articular surface. Conclusion: This case report describes a combined surgical approach for complex knee lesions that could represent a treatment option to avoid or at least delay posttraumatic osteoarthritis and more invasive procedures.

Original languageEnglish
Pages (from-to)288-292
Number of pages5
Issue number3
Publication statusPublished - Jul 2012


  • complex knee lesion
  • dynamic external fixator
  • osteochondral scaffold

ASJC Scopus subject areas

  • Immunology and Allergy
  • Biomedical Engineering
  • Physical Therapy, Sports Therapy and Rehabilitation


Dive into the research topics of 'Midterm Results of a Combined Biological and Mechanical Approach for the Treatment of a Complex Knee Lesion'. Together they form a unique fingerprint.

Cite this