Migraine-like disorder segregating with mtDNA 14484 Leber hereditary optic neuropathy mutation

L. M. Cupini; R. Massa; R. Floris; G. Manenti; B. Martini; A. Tessa; G. Nappi; G. Bernardi; F. M. Santorelli

Migraine-like disorder segregating with mtDNA 14484 Leber hereditary optic neuropathy mutation

L. M. Cupini, R. Massa, R. Floris, G. Manenti, B. Martini, A. Tessa, G. Nappi, G. Bernardi, F. M. Santorelli

Research output: Contribution to journal › Article › peer-review

Abstract

The authors report neurologic features in a large family harboring the mitochondrial DNA (mtDNA) mutation T14484C associated with Leber hereditary optic neuropathy (LHON). In the maternal line the mtDNA mutation was associated with optic neuropathy or migraine with aura or without aura and transient neurologic/visual disturbances. The segregation of familiar cases of migraine and LHON mutation broadens the clinical phenotype associated with a primary LHON mutation.

Original language	English
Pages (from-to)	717-719
Number of pages	3
Journal	Neurology
Volume	60
Issue number	4
Publication status	Published - Feb 25 2003

ASJC Scopus subject areas

Neuroscience(all)

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title = "Migraine-like disorder segregating with mtDNA 14484 Leber hereditary optic neuropathy mutation",

abstract = "The authors report neurologic features in a large family harboring the mitochondrial DNA (mtDNA) mutation T14484C associated with Leber hereditary optic neuropathy (LHON). In the maternal line the mtDNA mutation was associated with optic neuropathy or migraine with aura or without aura and transient neurologic/visual disturbances. The segregation of familiar cases of migraine and LHON mutation broadens the clinical phenotype associated with a primary LHON mutation.",

author = "Cupini, {L. M.} and R. Massa and R. Floris and G. Manenti and B. Martini and A. Tessa and G. Nappi and G. Bernardi and Santorelli, {F. M.}",

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T1 - Migraine-like disorder segregating with mtDNA 14484 Leber hereditary optic neuropathy mutation

AU - Cupini, L. M.

AU - Massa, R.

AU - Floris, R.

AU - Manenti, G.

AU - Martini, B.

AU - Tessa, A.

AU - Nappi, G.

AU - Bernardi, G.

AU - Santorelli, F. M.

PY - 2003/2/25

Y1 - 2003/2/25

N2 - The authors report neurologic features in a large family harboring the mitochondrial DNA (mtDNA) mutation T14484C associated with Leber hereditary optic neuropathy (LHON). In the maternal line the mtDNA mutation was associated with optic neuropathy or migraine with aura or without aura and transient neurologic/visual disturbances. The segregation of familiar cases of migraine and LHON mutation broadens the clinical phenotype associated with a primary LHON mutation.

AB - The authors report neurologic features in a large family harboring the mitochondrial DNA (mtDNA) mutation T14484C associated with Leber hereditary optic neuropathy (LHON). In the maternal line the mtDNA mutation was associated with optic neuropathy or migraine with aura or without aura and transient neurologic/visual disturbances. The segregation of familiar cases of migraine and LHON mutation broadens the clinical phenotype associated with a primary LHON mutation.

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ER -

Migraine-like disorder segregating with mtDNA 14484 Leber hereditary optic neuropathy mutation

Abstract

ASJC Scopus subject areas

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