TY - JOUR
T1 - Migraine, stroke and patent foramen ovale
T2 - A dangerous trio?
AU - Butera, Gianfranco
AU - Agostoni, Elio
AU - Biondi-Zoccai, Giuseppe
AU - Bresolin, Nereo
AU - Fumagalli, Lorenzo
AU - Chessa, Massimo
AU - Gallanti, Andrea
AU - Scacciatela, Paolo
AU - Carminati, Mario
PY - 2008/3
Y1 - 2008/3
N2 - The relationship between migraine, stroke and patent foramen ovale (PFO) has been the subject of considerable research efforts. Indeed, a lot of interest has focused on the potential benefits of percutaneous PFO closure. The aim of this article is to review data from the currently available literature. A total of 10 relevant studies were found in the literature, for a total of 1038 patients undergoing percutaneous PFO closure after events of cryptogenic stroke. Thirty-eight percent of these patients suffered from migraine. Combining the results of the available studies, 72% of patients were cured or improved significantly. Analysing the results according to migraine type, 81% of patients with migraine with aura had complete resolution or significantly improved as compared to 72% of patients with migraine without aura. Several limitations and drawbacks exist, however, and they are extensively discussed in this paper.
AB - The relationship between migraine, stroke and patent foramen ovale (PFO) has been the subject of considerable research efforts. Indeed, a lot of interest has focused on the potential benefits of percutaneous PFO closure. The aim of this article is to review data from the currently available literature. A total of 10 relevant studies were found in the literature, for a total of 1038 patients undergoing percutaneous PFO closure after events of cryptogenic stroke. Thirty-eight percent of these patients suffered from migraine. Combining the results of the available studies, 72% of patients were cured or improved significantly. Analysing the results according to migraine type, 81% of patients with migraine with aura had complete resolution or significantly improved as compared to 72% of patients with migraine without aura. Several limitations and drawbacks exist, however, and they are extensively discussed in this paper.
KW - Migraine
KW - Patent foramen ovale
KW - Stroke
KW - Transcatheter closure
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U2 - 10.2459/JCM.0b013e3282058912
DO - 10.2459/JCM.0b013e3282058912
M3 - Article
C2 - 18301138
AN - SCOPUS:40049109524
VL - 9
SP - 233
EP - 238
JO - Journal of Cardiovascular Medicine
JF - Journal of Cardiovascular Medicine
SN - 1558-2027
IS - 3
ER -