Migration, socio-economic status and the risk of colorectal cancer in Italy

F. E. Pisa, F. Barbone, M. Montella, R. Talamini, C. La Vecchia, S. Franceschi

Research output: Contribution to journalArticle

Abstract

To assess how the risk of cancer of the colon and rectum relates to place of birth and socio-economic status, we analysed data from an Italian case-control study. Data included 1225 cases with a recent diagnosis of cancer of the colon (ages 19-74 years), 728 cases of cancer of the rectum (ages 23-74 years) and 4154 controls (ages 19-74 years), frequency-matched with cases by age and catchment area and admitted to hospitals for a wide spectrum of acute non-neoplastic conditions. Compared with residents born in the north of Italy, migrants from the centre and south had an odds ratio (OR) of 0.7 (95% CI 0.5-0.9) for colon cancer and OR of 0.9 (95% CI 0.7-1.2) for cancer of the rectum. The inverse association of migration with colon cancer was stronger among women (OR 0.5, 95% CI 0.4-0.8) than among men (OR 0.8, 95% CI 0.6-1.1), and was independent of education and occupation. Among migrants, the direct association between education and colon cancer risk was less clear than among non-migrants. In conclusion, place of origin played an independent role in colon cancer aetiology. Results on rectal cancer were less clear, although in the same direction. Among migrants, those less susceptible to behavioural changes (e.g. women) retained most of the benefit associated with their place of origin.

Original languageEnglish
Pages (from-to)409-416
Number of pages8
JournalEuropean Journal of Cancer Prevention
Volume9
Issue number6
DOIs
Publication statusPublished - 2000

Keywords

  • Colorectal cancer
  • Migration
  • Socio-economic status

ASJC Scopus subject areas

  • Cancer Research
  • Oncology

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