Mild ciguatera poisoning: Case reports with neurophysiological evaluations

Raffaella Butera, Leon D. Prockop, Michelangelo Buonocore, Carlo Locatelli, Cristiano Gandini, Luigi Manzo

Research output: Contribution to journalArticle

Abstract

Ciguatera poisoning causes mainly gastrointestinal and neurological effects of variable severity. However, symptoms of peripheral neuropathy with paresthesias and paradoxical disturbance of thermal sensation are the hallmark. Electrophysiological studies are often normal, except in severe cases. We report four people who developed mild ciguatera poisoning after barracuda ingestion. Electrophysiological studies documented normocalcemic latent tetany. These findings are consistent with ciguatoxin's mechanism of toxicity, which involves inactivation of voltage-gated Na+ channels and eventually increases nerve membrane excitability. (C) 2000 John Wiley and Sons, Inc.

Original languageEnglish
Pages (from-to)1598-1603
Number of pages6
JournalMuscle and Nerve
Volume23
Issue number10
DOIs
Publication statusPublished - 2000

Fingerprint

Ciguatera Poisoning
Ciguatoxins
Tetany
Paresthesia
Peripheral Nervous System Diseases
Eating
Hot Temperature
Membranes

Keywords

  • Ciguatera fish poisoning
  • Latent tetany
  • Mannitol
  • Nerve conduction
  • Peripheral neuropathy

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Mild ciguatera poisoning : Case reports with neurophysiological evaluations. / Butera, Raffaella; Prockop, Leon D.; Buonocore, Michelangelo; Locatelli, Carlo; Gandini, Cristiano; Manzo, Luigi.

In: Muscle and Nerve, Vol. 23, No. 10, 2000, p. 1598-1603.

Research output: Contribution to journalArticle

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