Mild cutaneous reactions to drugs

Giuseppe Crisafulli, Fabrizio Franceschini, Silvia Caimmi, Paolo Bottau, Lucia Liotti, Francesca Saretta, Roberto Bernardini, Fabio Cardinale, Francesca Mori, Carlo Caffarelli

Research output: Contribution to journalReview articlepeer-review


Adverse reactions to drugs are not frequent in childhood. Cutaneous reactions are the most frequent in this age group. Mild cutaneous reactions are immediate or delayed adverse reactions that do not seriously compromise the clinical condition of children. The patients usually early improve and recover the state of health. Although it is difficult to define the prevalence accurately, we could affirm that the rate adverse reaction to drugs are often over estimated by both the families and the physicians. Therefore, children may be prone to loss of school days and inappropriate or sub-optimal treatments. However, the identification of a true adverse reaction to drugs allows adequate treatment and alert to further exposure to harmful drugs. (

Original languageEnglish
Pages (from-to)36-43
Number of pages8
JournalActa Biomedica
Publication statusPublished - Jan 1 2019


  • Children
  • Drug hypersensitivity reactions
  • Drug provocation test
  • Exanthemaurticaria
  • Skin test
  • Specific IgE

ASJC Scopus subject areas

  • Medicine(all)


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