Miller's seminal studies on the role of thymus in immunity

D. Ribatti, E. Crivellato, A. Vacca

Research output: Contribution to journalArticlepeer-review


The thymus is one of the two primary lymphoid organs. It is responsible for the provision of T lymphocytes to the entire body, and provides a unique microenvironment in which T cell precursors (thymocytes) undergo development, differentiation and clonal expansion. This review article summarizes the seminal work of the Australian scientist Francis Albert Pierre Miller concerning the description for the first time of the crucial role of the thymus for normal development of the immune system.

Original languageEnglish
Pages (from-to)371-375
Number of pages5
JournalClinical and Experimental Immunology
Issue number3
Publication statusPublished - Jun 2006


  • History of medicine
  • Immunology
  • Thymus

ASJC Scopus subject areas

  • Immunology


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