Abstract
Chronic migraine (CM) is a disabling condition arising from a complex mixture of interconnected biological, psychological and social factors, and is often associated with medication overuse (MO). Mindfulness is emerging as a helpful treatment for pain, and one study showed that the longitudinal 12 months’ course of CM-MO patients that attended mindfulness-based treatment alone was similar to that of patients receiving medical prophylaxis alone; in this study, we describe the course of biomarkers of inflammation. Our results provide initial evidence of sustained similar effects on reduced concentration of biomarkers of inflammation, although not sizeable enough to reach statistical significance. Whether more intensive treatment and/or larger samples would lead to greater changes is unknown, but these encouraging preliminary findings suggest further research is warranted.
| Original language | English |
|---|---|
| Pages (from-to) | 173-175 |
| Number of pages | 3 |
| Journal | Neurological Sciences |
| Volume | 38 |
| DOIs | |
| Publication status | Published - May 1 2017 |
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Keywords
- Biomarkers
- Chronic migraine
- Interleukin-6
- Medication overuse
- Mindfulness
ASJC Scopus subject areas
- Dermatology
- Clinical Neurology
- Psychiatry and Mental health
Cite this
Mindfulness and pharmacological prophylaxis have comparable effect on biomarkers of inflammation and clinical indexes in chronic migraine with medication overuse : results at 12 months after withdrawal. / Grazzi, Licia; D’Amico, Domenico; Raggi, Alberto; Leonardi, Matilde; Ciusani, Emilio; Corsini, Elena; D’Andrea, Giovanni; Bolner, Andrea; Salgado-García, Francisco; Andrasik, Frank; Sansone, Emanuela.
In: Neurological Sciences, Vol. 38, 01.05.2017, p. 173-175.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mindfulness and pharmacological prophylaxis have comparable effect on biomarkers of inflammation and clinical indexes in chronic migraine with medication overuse
T2 - results at 12 months after withdrawal
AU - Grazzi, Licia
AU - D’Amico, Domenico
AU - Raggi, Alberto
AU - Leonardi, Matilde
AU - Ciusani, Emilio
AU - Corsini, Elena
AU - D’Andrea, Giovanni
AU - Bolner, Andrea
AU - Salgado-García, Francisco
AU - Andrasik, Frank
AU - Sansone, Emanuela
PY - 2017/5/1
Y1 - 2017/5/1
N2 - Chronic migraine (CM) is a disabling condition arising from a complex mixture of interconnected biological, psychological and social factors, and is often associated with medication overuse (MO). Mindfulness is emerging as a helpful treatment for pain, and one study showed that the longitudinal 12 months’ course of CM-MO patients that attended mindfulness-based treatment alone was similar to that of patients receiving medical prophylaxis alone; in this study, we describe the course of biomarkers of inflammation. Our results provide initial evidence of sustained similar effects on reduced concentration of biomarkers of inflammation, although not sizeable enough to reach statistical significance. Whether more intensive treatment and/or larger samples would lead to greater changes is unknown, but these encouraging preliminary findings suggest further research is warranted.
AB - Chronic migraine (CM) is a disabling condition arising from a complex mixture of interconnected biological, psychological and social factors, and is often associated with medication overuse (MO). Mindfulness is emerging as a helpful treatment for pain, and one study showed that the longitudinal 12 months’ course of CM-MO patients that attended mindfulness-based treatment alone was similar to that of patients receiving medical prophylaxis alone; in this study, we describe the course of biomarkers of inflammation. Our results provide initial evidence of sustained similar effects on reduced concentration of biomarkers of inflammation, although not sizeable enough to reach statistical significance. Whether more intensive treatment and/or larger samples would lead to greater changes is unknown, but these encouraging preliminary findings suggest further research is warranted.
KW - Biomarkers
KW - Chronic migraine
KW - Interleukin-6
KW - Medication overuse
KW - Mindfulness
UR - http://www.scopus.com/inward/record.url?scp=85019626897&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85019626897&partnerID=8YFLogxK
U2 - 10.1007/s10072-017-2874-0
DO - 10.1007/s10072-017-2874-0
M3 - Article
AN - SCOPUS:85019626897
VL - 38
SP - 173
EP - 175
JO - Neurological Sciences
JF - Neurological Sciences
SN - 1590-1874
ER -