Minimally invasive closure of patent foramen ovale through port-access surgery

P. Spreafico, M. Rinaldi, A. Alloni, S. Perrotta, F. Grasselli, M. Viganò

Research output: Contribution to journalArticlepeer-review


We present here our experience of patent foramen ovale closure through a mini-invasive surgical technique. With the new surgical platform termed Heartport System, it is possible to install extra-corporeal circulation and to obtain cardioplegic arrest of the heart with endovascular techniques. This allows the operation of closure to be entirely performed through a micro-thoracotomy (Port-access surgery) in the right 4th intercostal space. Sixty-one patients underwent this surgical correction and seventeen of them (26%) had a diagnosis of patent foramen ovale, 12 with an history of cerebrovascular accidents. They are all alive and well after a mean follow-up of 16 months, with no recurrence of the inter-atrial communication and free from new neurological events. The post-operative course was uneventful with patients discharged on postoperative day 4. This technique shows a 100% efficacy, minimise surgical trauma, allows a quick recovery and offers excellent cosmetic results with no scarring. We believe that this procedure must be regarded as the "golden standard" for the closure of atrial septal defects.

Original languageEnglish
JournalNeurological Sciences
Issue numberSUPPL. 1
Publication statusPublished - May 2003


  • Atrial septal defect
  • Cryptogenic stroke
  • Mini-invasive cardiac surgery
  • Patent foramen ovale
  • Port-access surgery

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology


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