Minimally invasive procedures for the management of vertebral bone pain due to cancer: The EAPC recommendations

Sebastiano Mercadante, Pål Klepstad, Geana Paula Kurita, Per Sjøgren, Alessandra Pigni, Augusto Caraceni

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Image-guided percutaneous ablation methods have proved effective for treatment of benign bone tumors and for palliation of metastases involving the bone. However, the role of these techniques is controversial and has to be better defined in the setting of palliative care. Methods: A systematic review of the existing data regarding minimally invasive techniques for the pain management of vertebral bone metastases was performed by experts of the European Palliative Care Research Network. Results: Only five papers were taken into consideration after performing rigorous screening according to inclusion and exclusion criteria (low number of patients, retrospective series, proceedings). Discussion: According to the present data a recommendation should be made to perform kiphoplasty in patients with vertebral tumors or metastases. However, the strength of this recommendation was based on one randomized controlled study. Several weaknesses and low quality of study design were observed with other techniques. Conclusion: Further randomized controlled trials are required to improve the strength of evidence available to suggest these procedures on large scale. Until then, the balance of evidence favors the use of these procedures in a small select cohort of patients with severe and disabling back pain refractory to medical therapy.

Original languageEnglish
Pages (from-to)129-133
Number of pages5
JournalActa Oncologica
Volume55
Issue number2
DOIs
Publication statusPublished - Feb 1 2016

Fingerprint

Bone and Bones
Pain
Neoplasm Metastasis
Palliative Care
Neoplasms
Pain Management
Back Pain
Randomized Controlled Trials
Therapeutics
Research

ASJC Scopus subject areas

  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Hematology

Cite this

Minimally invasive procedures for the management of vertebral bone pain due to cancer : The EAPC recommendations. / Mercadante, Sebastiano; Klepstad, Pål; Paula Kurita, Geana; Sjøgren, Per; Pigni, Alessandra; Caraceni, Augusto.

In: Acta Oncologica, Vol. 55, No. 2, 01.02.2016, p. 129-133.

Research output: Contribution to journalArticle

Mercadante, Sebastiano ; Klepstad, Pål ; Paula Kurita, Geana ; Sjøgren, Per ; Pigni, Alessandra ; Caraceni, Augusto. / Minimally invasive procedures for the management of vertebral bone pain due to cancer : The EAPC recommendations. In: Acta Oncologica. 2016 ; Vol. 55, No. 2. pp. 129-133.
@article{4c5ae8fca4ec4589a313ee303f4c33a5,
title = "Minimally invasive procedures for the management of vertebral bone pain due to cancer: The EAPC recommendations",
abstract = "Background: Image-guided percutaneous ablation methods have proved effective for treatment of benign bone tumors and for palliation of metastases involving the bone. However, the role of these techniques is controversial and has to be better defined in the setting of palliative care. Methods: A systematic review of the existing data regarding minimally invasive techniques for the pain management of vertebral bone metastases was performed by experts of the European Palliative Care Research Network. Results: Only five papers were taken into consideration after performing rigorous screening according to inclusion and exclusion criteria (low number of patients, retrospective series, proceedings). Discussion: According to the present data a recommendation should be made to perform kiphoplasty in patients with vertebral tumors or metastases. However, the strength of this recommendation was based on one randomized controlled study. Several weaknesses and low quality of study design were observed with other techniques. Conclusion: Further randomized controlled trials are required to improve the strength of evidence available to suggest these procedures on large scale. Until then, the balance of evidence favors the use of these procedures in a small select cohort of patients with severe and disabling back pain refractory to medical therapy.",
author = "Sebastiano Mercadante and P{\aa}l Klepstad and {Paula Kurita}, Geana and Per Sj{\o}gren and Alessandra Pigni and Augusto Caraceni",
year = "2016",
month = "2",
day = "1",
doi = "10.3109/0284186X.2015.1073351",
language = "English",
volume = "55",
pages = "129--133",
journal = "Acta Oncologica",
issn = "0284-186X",
publisher = "Informa Healthcare",
number = "2",

}

TY - JOUR

T1 - Minimally invasive procedures for the management of vertebral bone pain due to cancer

T2 - The EAPC recommendations

AU - Mercadante, Sebastiano

AU - Klepstad, Pål

AU - Paula Kurita, Geana

AU - Sjøgren, Per

AU - Pigni, Alessandra

AU - Caraceni, Augusto

PY - 2016/2/1

Y1 - 2016/2/1

N2 - Background: Image-guided percutaneous ablation methods have proved effective for treatment of benign bone tumors and for palliation of metastases involving the bone. However, the role of these techniques is controversial and has to be better defined in the setting of palliative care. Methods: A systematic review of the existing data regarding minimally invasive techniques for the pain management of vertebral bone metastases was performed by experts of the European Palliative Care Research Network. Results: Only five papers were taken into consideration after performing rigorous screening according to inclusion and exclusion criteria (low number of patients, retrospective series, proceedings). Discussion: According to the present data a recommendation should be made to perform kiphoplasty in patients with vertebral tumors or metastases. However, the strength of this recommendation was based on one randomized controlled study. Several weaknesses and low quality of study design were observed with other techniques. Conclusion: Further randomized controlled trials are required to improve the strength of evidence available to suggest these procedures on large scale. Until then, the balance of evidence favors the use of these procedures in a small select cohort of patients with severe and disabling back pain refractory to medical therapy.

AB - Background: Image-guided percutaneous ablation methods have proved effective for treatment of benign bone tumors and for palliation of metastases involving the bone. However, the role of these techniques is controversial and has to be better defined in the setting of palliative care. Methods: A systematic review of the existing data regarding minimally invasive techniques for the pain management of vertebral bone metastases was performed by experts of the European Palliative Care Research Network. Results: Only five papers were taken into consideration after performing rigorous screening according to inclusion and exclusion criteria (low number of patients, retrospective series, proceedings). Discussion: According to the present data a recommendation should be made to perform kiphoplasty in patients with vertebral tumors or metastases. However, the strength of this recommendation was based on one randomized controlled study. Several weaknesses and low quality of study design were observed with other techniques. Conclusion: Further randomized controlled trials are required to improve the strength of evidence available to suggest these procedures on large scale. Until then, the balance of evidence favors the use of these procedures in a small select cohort of patients with severe and disabling back pain refractory to medical therapy.

UR - http://www.scopus.com/inward/record.url?scp=84956625793&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84956625793&partnerID=8YFLogxK

U2 - 10.3109/0284186X.2015.1073351

DO - 10.3109/0284186X.2015.1073351

M3 - Article

AN - SCOPUS:84956625793

VL - 55

SP - 129

EP - 133

JO - Acta Oncologica

JF - Acta Oncologica

SN - 0284-186X

IS - 2

ER -