MINT: The Molecular INTeraction database

Andrew Chatr-aryamontri, Arnaud Ceol, Luisa Montecchi Palazzi, Giuliano Nardelli, Maria Victoria Schneider, Luisa Castagnoli, Gianni Cesareni

Research output: Contribution to journalArticle

Abstract

The Molecular INTeraction database (MINT, http://mint.bio.uniroma2.it/ mint/) aims at storing, in a structured format, information about molecular interactions (MIs) by extracting experimental details from work published in peer-reviewed journals. At present the MINT team focuses the curation work on physical interactions between proteins. Genetic or computationally inferred interactions are not included in the database. Over the past four years MINT has undergone extensive revision. The new version of MINT is based on a completely remodeled database structure, which offers more efficient data exploration and analysis, and is characterized by entries with a richer annotation. Over the past few years the number of curated physical interactions has soared to over 95 000. The whole dataset can be freely accessed online in both interactive and batch modes through web-based interfaces and an FTP server. MINT now includes, as an integrated addition, HomoMINT, a database of interactions between human proteins inferred from experiments with ortholog proteins in model organisms (http://mint.bio.uniroma2.it/mint/).

Original languageEnglish
JournalNucleic Acids Research
Volume35
Issue numberSUPPL. 1
DOIs
Publication statusPublished - Jan 2007

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ASJC Scopus subject areas

  • Genetics

Cite this

Chatr-aryamontri, A., Ceol, A., Palazzi, L. M., Nardelli, G., Schneider, M. V., Castagnoli, L., & Cesareni, G. (2007). MINT: The Molecular INTeraction database. Nucleic Acids Research, 35(SUPPL. 1). https://doi.org/10.1093/nar/gkl950