MINT, the molecular interaction database: 2012 Update

Luana Licata, Leonardo Briganti, Daniele Peluso, Livia Perfetto, Marta Iannuccelli, Eugenia Galeota, Francesca Sacco, Anita Palma, Aurelio Pio Nardozza, Elena Santonico, Luisa Castagnoli, Gianni Cesareni

Research output: Contribution to journalArticlepeer-review

Abstract

The Molecular INTeraction Database (MINT, http://mint.bio.uniroma2.it/mint/ ) is a public repository for protein-protein interactions (PPI) reported in peer-reviewed journals. The database grows steadily over the years and at September 2011 contains approximately 235 000 binary interactions captured from over 4750 publications. The web interface allows the users to search, visualize and download interactions data. MINT is one of the members of the International Molecular Exchange consortium (IMEx) and adopts the Molecular Interaction Ontology of the Proteomics Standard Initiative (PSI-MI) standards for curation and data exchange. MINT data are freely accessible and downloadable at http://mint.bio.uniroma2.it/mint/download.do. We report here the growth of the database, the major changes in curation policy and a new algorithm to assign a confidence to each interaction.

Original languageEnglish
JournalNucleic Acids Research
Volume40
Issue numberD1
DOIs
Publication statusPublished - Jan 2012

ASJC Scopus subject areas

  • Genetics

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