Misidentification Delusions: Prevalence in Different Types of Dementia and Validation of a Structured Questionnaire

Giulia Perini, Alessandro Carlini, Simone Pomati, Margherita Alberoni, Claudio Mariani, Raffaello Nemni, Elisabetta Farina

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Misidentification delusions (MDs) are considered relatively rare psychopathologic phenomena that may occur within the context of psychiatric or neurological conditions. The purpose of this study was to assess the prevalence of MD in different types of dementia, correlate the presence of MD with demographic and clinical variables, and validate a specific questionnaire. We examined 146 subjects with Alzheimer disease, 21 with Lewy body dementia, 6 with frontotemporal dementia, and 13 with vascular dementia (subcortical type), who were consecutively enrolled in the study from 2 Memory Clinics. Patients had a mean age of 78.7±6.4 years and an Mini-Mental State Examination average score of 16.9±6.1. The Neuropsychiatric Inventory delusion subscale and a new Misidentification Delusion Questionnaire aimed at specific assessment of 11 delusional misidentification syndromes were administrated to the caregivers. On the basis of the Neuropsychiatric Inventory, MDs were present in 33.3% of the subjects, whereas according to the Misidentification Delusion Questionnaire they were present in 36.0% of the subjects. Specifically, 34.2% of Alzheimer disease, 52.4% of Lewy body dementia, and 46.1% of vascular dementia patients experienced at least 1 MD. None of the patients with frontotemporal dementia developed MD. The most frequent MD was house misidentification, followed by splitting of people and reduplicative paramnesia. Our self-administered questionnaire proved to be an accurate and specific tool for the detection of MD.

Original languageEnglish
JournalAlzheimer Disease and Associated Disorders
DOIs
Publication statusPublished - Oct 2016

Fingerprint

Delusions
Dementia
Lewy Body Disease
Frontotemporal Dementia
Vascular Dementia
Alzheimer Disease
Surveys and Questionnaires
Equipment and Supplies
Caregivers
Psychiatry
Demography

ASJC Scopus subject areas

  • Geriatrics and Gerontology
  • Psychiatry and Mental health
  • Gerontology
  • Clinical Psychology

Cite this

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title = "Misidentification Delusions: Prevalence in Different Types of Dementia and Validation of a Structured Questionnaire",
abstract = "Misidentification delusions (MDs) are considered relatively rare psychopathologic phenomena that may occur within the context of psychiatric or neurological conditions. The purpose of this study was to assess the prevalence of MD in different types of dementia, correlate the presence of MD with demographic and clinical variables, and validate a specific questionnaire. We examined 146 subjects with Alzheimer disease, 21 with Lewy body dementia, 6 with frontotemporal dementia, and 13 with vascular dementia (subcortical type), who were consecutively enrolled in the study from 2 Memory Clinics. Patients had a mean age of 78.7±6.4 years and an Mini-Mental State Examination average score of 16.9±6.1. The Neuropsychiatric Inventory delusion subscale and a new Misidentification Delusion Questionnaire aimed at specific assessment of 11 delusional misidentification syndromes were administrated to the caregivers. On the basis of the Neuropsychiatric Inventory, MDs were present in 33.3{\%} of the subjects, whereas according to the Misidentification Delusion Questionnaire they were present in 36.0{\%} of the subjects. Specifically, 34.2{\%} of Alzheimer disease, 52.4{\%} of Lewy body dementia, and 46.1{\%} of vascular dementia patients experienced at least 1 MD. None of the patients with frontotemporal dementia developed MD. The most frequent MD was house misidentification, followed by splitting of people and reduplicative paramnesia. Our self-administered questionnaire proved to be an accurate and specific tool for the detection of MD.",
author = "Giulia Perini and Alessandro Carlini and Simone Pomati and Margherita Alberoni and Claudio Mariani and Raffaello Nemni and Elisabetta Farina",
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AU - Alberoni, Margherita

AU - Mariani, Claudio

AU - Nemni, Raffaello

AU - Farina, Elisabetta

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