Mismatch of neurophysiological findings in partial recovery of consciousness: A case report

Francesca Pistoia, Simona Sacco, Raffaele Palmirotta, Paolo Onorati, Antonio Carolei, Marco Sarà

Research output: Contribution to journalArticle

Abstract

Aim: Electroencephalography (EEG) and somatosensory potentials (SEP) are regarded as useful tools for exploring residual brain activity and providing information for recovery in patients with anoxic encephalopaty. However, the diagnoses of vegetative and minimally conscious states can only be made by means of repeated specific neurological examinations. In this respect, this study describes the case of a patient with mismatch of neurophysiological findings despite partial recovery to a minimally conscious state. Case report: A 52-year-old man was admitted to the Post-Coma Intensive and Rehabilitation Care Unit with a diagnosis of anoxic encephalopathy. EEG, according to Hockaday, was severely abnormal (Grade IVa). SEP showed bilateral loss of all cortical components. Four weeks after admission the Coma Recovery Scale Revised (CRS-R) score moved from 7/23 to 13/23. Conclusions: This patient persistently showed a mismatch of neurophysiological findings which did not anticipate the slight but discriminating improvement ascertained through the neurological examination. This observation confirms that electrophysiological evaluations can only be regarded as ancillary tools since level of consciousness may be reliably evaluated only by means of repeated specific neurological assessments. As this case-report suggests, neurophysiological findings may turn out to be inconclusive and misleading in relation to the assessment of consciousness and may lead to an underestimate of minimal signs of recovery across the grey-zone from the vegetative to the minimally conscious state.

Original languageEnglish
Pages (from-to)633-637
Number of pages5
JournalBrain Injury
Volume22
Issue number7-8
DOIs
Publication statusPublished - Jul 2008

Keywords

  • Disorders of consciousness
  • Electroencephalography
  • Somatosensory potentials

ASJC Scopus subject areas

  • Clinical Neurology

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    Pistoia, F., Sacco, S., Palmirotta, R., Onorati, P., Carolei, A., & Sarà, M. (2008). Mismatch of neurophysiological findings in partial recovery of consciousness: A case report. Brain Injury, 22(7-8), 633-637. https://doi.org/10.1080/02699050802189693