Abstract
Purpose - To evaluate the risk of having a baby with congenital anomalies in mothers who used misoprostol during pregnancy. Methods - Hospital-based case-control study from Hospital Chateaubriand, Fortaleza, Brasil. Cases were 37 babies weighing less than 1500 g with congenital anomalies of various types, and the comparison group included 387 infants also weighing less than 1500 g, and without congenital anomalies. Results - The multivariate odds ratio of having a baby with congenital anomalies was 2.4 (95% confidence interval 1.0-6.2) in mothers who reported having used misoprostol compared with those who did not. Conclusions - Misoprostol use during pregnancy might be related to a broad spectrum of congenital anomalies in infants. Copyright (C) 2000 John Wiley and Sons, Ltd.
Original language | English |
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Pages (from-to) | 401-403 |
Number of pages | 3 |
Journal | Pharmacoepidemiology and Drug Safety |
Volume | 9 |
Issue number | 5 |
DOIs | |
Publication status | Published - 2000 |
Keywords
- Congenital anomalies
- Induced abortions
- Low birth weight
- Misoprostol
- Risk
ASJC Scopus subject areas
- Pharmacology (medical)
- Pharmacology, Toxicology and Pharmaceutics(all)