TY - JOUR
T1 - Mitochondrial Proteins Coded by Human Tumor Viruses
AU - Cavallari, Ilaria
AU - Scattolin, Gloria
AU - Silic-Benussi, Micol
AU - Raimondi, Vittoria
AU - D'Agostino, Donna M
AU - Ciminale, Vincenzo
PY - 2018
Y1 - 2018
N2 - Viruses must exploit the cellular biosynthetic machinery and evade cellular defense systems to complete their life cycles. Due to their crucial roles in cellular bioenergetics, apoptosis, innate immunity and redox balance, mitochondria are important functional targets of many viruses, including tumor viruses. The present review describes the interactions between mitochondria and proteins coded by the human tumor viruses human T-cell leukemia virus type 1, Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus, human hepatitis viruses B and C, and human papillomavirus, and highlights how these interactions contribute to viral replication, persistence and transformation.
AB - Viruses must exploit the cellular biosynthetic machinery and evade cellular defense systems to complete their life cycles. Due to their crucial roles in cellular bioenergetics, apoptosis, innate immunity and redox balance, mitochondria are important functional targets of many viruses, including tumor viruses. The present review describes the interactions between mitochondria and proteins coded by the human tumor viruses human T-cell leukemia virus type 1, Epstein-Barr virus, Kaposi's sarcoma-associated herpesvirus, human hepatitis viruses B and C, and human papillomavirus, and highlights how these interactions contribute to viral replication, persistence and transformation.
U2 - 10.3389/fmicb.2018.00081
DO - 10.3389/fmicb.2018.00081
M3 - Review article
C2 - 29467726
VL - 9
SP - 81
JO - Frontiers in Microbiology
JF - Frontiers in Microbiology
SN - 1664-302X
ER -