MitraClip procedure as ‘bridge to list’, the ultimate therapeutic option for end-stage heart failure patients not eligible for heart transplantation due to severe pulmonary hypertension

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1 Citation (Scopus)

Abstract

Patients with end-stage heart failure (HF), pulmonary hypertension and elevated pulmonary vascular resistance (PVR) despite medical therapy are not eligible for heart transplantation (HTx). In this ‘proof of concept’ case series, we demonstrate the feasibility and efficacy of the MitraClip procedure as ‘bridge to list’ in end-stage HF patients not eligible for HTx. In fact, in the three patients reported, who were initially excluded from the HTx list because of elevated PVR, the MitraClip procedure was followed by a sustained improvement of PVR, allowing the patients’ risk to be reclassified, and they were then considered eligible for HTx.

Original languageEnglish
JournalPulmonary Circulation
Volume8
Issue number4
DOIs
Publication statusPublished - Oct 1 2018

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Heart Transplantation
Pulmonary Hypertension
Heart Failure
Vascular Resistance
Therapeutics

Keywords

  • end-stage heart failure
  • heart transplantation
  • MitraClip procedure
  • mitral regurgitation

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

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abstract = "Patients with end-stage heart failure (HF), pulmonary hypertension and elevated pulmonary vascular resistance (PVR) despite medical therapy are not eligible for heart transplantation (HTx). In this ‘proof of concept’ case series, we demonstrate the feasibility and efficacy of the MitraClip procedure as ‘bridge to list’ in end-stage HF patients not eligible for HTx. In fact, in the three patients reported, who were initially excluded from the HTx list because of elevated PVR, the MitraClip procedure was followed by a sustained improvement of PVR, allowing the patients’ risk to be reclassified, and they were then considered eligible for HTx.",
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author = "Gabriele Crimi and Valeria Gritti and Stefano Ghio and Valeria Crescio and Giulia Magrini and Laura Scelsi and Annalisa Turco and Fabrizio Gazzoli and Maurizio Ferrario and Claudia Raineri and {Oltrona Visconti}, Luigi",
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AU - Crimi, Gabriele

AU - Gritti, Valeria

AU - Ghio, Stefano

AU - Crescio, Valeria

AU - Magrini, Giulia

AU - Scelsi, Laura

AU - Turco, Annalisa

AU - Gazzoli, Fabrizio

AU - Ferrario, Maurizio

AU - Raineri, Claudia

AU - Oltrona Visconti, Luigi

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