Mitral inflow patterns after mitraclip implantation at rest and during exercise

Kirsten Boerlage-Van Dijk, Annelieke C M J Van Riel, Rianne H A C M De Bruin-Bon, Esther M A Wiegerinck, Karel T. Koch, M. Marije Vis, Paola G. Meregalli, Navin R. Bindraban, Barbara J M Mulder, Jan J. Piek, Berto J. Bouma, Jan Baan

Research output: Contribution to journalArticlepeer-review


Background MitraClip implantation reduces mitral regurgitation effectively but decreases mitral valve area, creating iatrogenic mitral stenosis. Evaluation with transesophageal echocardiography intraprocedurally is necessary to measure mitral regurgitation and mitral valve pressure gradient (MVPG) to determine whether it is necessary and safe to place more clips. The aim of this study was to investigate whether these intraprocedural hemodynamics represent postprocedural measurements and whether exercise is affected by the stenosis. Methods In this retrospective single-center study, 51 patients who underwent MitraClip implantation were included. Measurements were performed intraprocedurally using transesophageal echocardiography and postprocedurally using transthoracic echocardiography. In 23 of these patients, exercise echocardiography was performed at follow-up. Results Intraprocedural mean MVPG was 3.0 ± 1.6 mm Hg and increased to 4.3 ± 2.2 mm Hg postprocedurally (P

Original languageEnglish
JournalJournal of the American Society of Echocardiography
Issue number1
Publication statusPublished - 2014


  • MitraClip
  • Mitral regurgitation
  • Mitral valve pressure gradient
  • Transthoracic exercise echocardiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


Dive into the research topics of 'Mitral inflow patterns after mitraclip implantation at rest and during exercise'. Together they form a unique fingerprint.

Cite this