Mitral valve repair for functional mitral regurgitation: Is annuloplasty alone enough?

Ottavio Alfieri, Michele De Bonis

Research output: Contribution to journalArticlepeer-review


Purpose of Review: To outline indications and contraindications to mitral valve surgery in the clinical context of dilated cardiomyopathy and the surgical principles to follow in performing an undersized annuloplasty. Moreover, we will describe the characteristics of the patients for whom an annuloplasty alone is unlikely to provide an effective result and for whom, therefore, some other procedures or mitral valve replacement should be preferred. Recent Findings: In functional mitral regurgitation, competence of the mitral valve can be restored by using a restrictive annuloplasty. This procedure leads to symptomatic improvement and reverse left ventricular remodeling in a substantial proportion of patients. However, the failure rate of undersized annuloplasty is still high and is mainly due to inappropriate patient selection and to technical issues that have been progressively identified. Summary: In the treatment of functional mitral regurgitation, annuloplasty alone should only be carried out in the early phase of the disease before the occurrence of advanced left ventricular remodeling and echocardiographic predictors of unfavorable outcome should be taken into account. Under certain circumstances, surgery should include additional procedures apart from annuloplasty to enhance the durability of the repair. Mitral valve replacement should be considered when unsatisfactory results are expected with mitral valve repair due to advanced left ventricular remodeling and long-lasting heart failure.

Original languageEnglish
Pages (from-to)114-118
Number of pages5
JournalCurrent Opinion in Cardiology
Issue number2
Publication statusPublished - Mar 2010


  • Annuloplasty
  • Dilated cardiomyopathy
  • Mitral regurgitation
  • Mitral repair

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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