Abstract
An adult female with mixed connective tissue disease is described who had non-scarring alopecia, telangiectases, Raynaud's phenomenon and swollen hands. No clinical signs of SLE and only modest signs of myositis were present. High levels of RNP antibodies were detected in serum and direct immunofluorescence showed IgG staining of epidermal nuclei with a speckled pattern. Elution techniques performed on circulating lymphoid cells showed mixed features of both LE and scleroderma, namely antibodies to basal zone, to epidermal basal cells and to endothelial cells in mid-dermis.
| Original language | English |
|---|---|
| Pages (from-to) | 485-489 |
| Number of pages | 5 |
| Journal | Clinical and Experimental Dermatology |
| Volume | 7 |
| Issue number | 5 |
| Publication status | Published - 1982 |
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ASJC Scopus subject areas
- Dermatology
Cite this
Mixed immunofluorescence findings in mixed connective tissue disease. / Nunzi, E.; Parodi, A.; Rebora, A.
In: Clinical and Experimental Dermatology, Vol. 7, No. 5, 1982, p. 485-489.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Mixed immunofluorescence findings in mixed connective tissue disease
AU - Nunzi, E.
AU - Parodi, A.
AU - Rebora, A.
PY - 1982
Y1 - 1982
N2 - An adult female with mixed connective tissue disease is described who had non-scarring alopecia, telangiectases, Raynaud's phenomenon and swollen hands. No clinical signs of SLE and only modest signs of myositis were present. High levels of RNP antibodies were detected in serum and direct immunofluorescence showed IgG staining of epidermal nuclei with a speckled pattern. Elution techniques performed on circulating lymphoid cells showed mixed features of both LE and scleroderma, namely antibodies to basal zone, to epidermal basal cells and to endothelial cells in mid-dermis.
AB - An adult female with mixed connective tissue disease is described who had non-scarring alopecia, telangiectases, Raynaud's phenomenon and swollen hands. No clinical signs of SLE and only modest signs of myositis were present. High levels of RNP antibodies were detected in serum and direct immunofluorescence showed IgG staining of epidermal nuclei with a speckled pattern. Elution techniques performed on circulating lymphoid cells showed mixed features of both LE and scleroderma, namely antibodies to basal zone, to epidermal basal cells and to endothelial cells in mid-dermis.
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UR - http://www.scopus.com/inward/citedby.url?scp=0019913596&partnerID=8YFLogxK
M3 - Article
C2 - 6756713
AN - SCOPUS:0019913596
VL - 7
SP - 485
EP - 489
JO - Clinical and Experimental Dermatology
JF - Clinical and Experimental Dermatology
SN - 0307-6938
IS - 5
ER -