MMP-7 promoter polymorphisms do not influence CD4+ recovery and changes in plasma viral load during antiretroviral therapy for HIV-1 infection

E. Lugli, M. Pinti, M. Nasi, L. Troiano, N. Prada, C. Mussini, V. Borghi, R. Esposito, Andrea Cossarizza

Research output: Contribution to journalArticlepeer-review

Abstract

Matrix metalloproteinase-7 (MMP-7) generates soluble Fas Ligand (FasL), which is involved in the apoptotic loss of CD4+ T cells during HIV infection. We evaluated whether two polymorphisms in MMP-7 promoter could influence CD4+ recover in response to antiretroviral therapy, and found that these polymorphisms are ineffective.

Original languageEnglish
Pages (from-to)269-271
Number of pages3
JournalInternational Journal of Immunogenetics
Volume32
Issue number5
DOIs
Publication statusPublished - Oct 2005

ASJC Scopus subject areas

  • Genetics
  • Immunology
  • Molecular Biology

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