Mobile phone emissions and human brain excitability

Florinda Ferreri, Giuseppe Curcio, Patrizio Pasqualetti, Luigi De Gennaro, Rita Fini, Paolo Maria Rossini

Research output: Contribution to journalArticle

Abstract

Objective: To test-via Transcranial Magnetic Stimulation (TMS)-the excitability of each brain hemisphere after 'real' or 'sham' exposure to the electromagnetic field (EMF) generated by a mobile phone operating in the Global System for Mobile Communication (GSM). Methods: Fifteen male volunteers attended two experimental sessions, one week apart, in a cross-over, double-blind paradigm. In one session the signal was turned ON (EMF-on, real exposure), in the other it was turned OFF (EMF-off, sham exposure), for 45 minutes. Motor Evoked Potentials (MEPs) were recorded using a paired-pulse paradigm (testing intracortical excitability with 1 to 17 ms interstimulus intervals), both before and at different times after exposure to the EMF. Short Intracortical Inhibition (SICI) and Facilitation (ICF) curves were evaluated both on the exposed and non-exposed hemispheres. Tympanic temperature was collected during each session. Results: The intracortical excitability curve becomes significantly modified during real exposure, with SICI being reduced and ICF enhanced in the acutely exposed brain hemisphere as compared to the contralateral, non-exposed hemisphere or to sham exposure. Tympanic temperature showed no significant main effect or interactions. Interpretation: These results demonstrate that GSM-EMFs modify brain excitability. Possible implications and applications are discussed.

Original languageEnglish
Pages (from-to)188-196
Number of pages9
JournalAnnals of Neurology
Volume60
Issue number2
DOIs
Publication statusPublished - Aug 2006

ASJC Scopus subject areas

  • Neuroscience(all)

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    Ferreri, F., Curcio, G., Pasqualetti, P., De Gennaro, L., Fini, R., & Rossini, P. M. (2006). Mobile phone emissions and human brain excitability. Annals of Neurology, 60(2), 188-196. https://doi.org/10.1002/ana.20906